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Somatic mtDNA variation is an important component of Parkinson's disease

There is a growing body of evidence linking mitochondrial dysfunction, mediated either through inherited mitochondrial DNA (mtDNA) variation or mitochondrial proteomic deficit, to Parkinson's disease (PD). Yet, despite this, the role of somatic mtDNA point mutations and specifically point-mutat...

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Detalles Bibliográficos
Autores principales:	Coxhead, Jonathan, Kurzawa-Akanbi, Marzena, Hussain, Rafiqul, Pyle, Angela, Chinnery, Patrick, Hudson, Gavin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	Genetic Report Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759607/ https://www.ncbi.nlm.nih.gov/pubmed/26639157 http://dx.doi.org/10.1016/j.neurobiolaging.2015.10.036

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