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Heme oxygenase-1 induction attenuates imiquimod-induced psoriasiform inflammation by negative regulation of Stat3 signaling

Heme oxygenase-1 (HO-1), a stress-inducible protein with a potential anti-inflammatory effect, plays an important role in skin injury and wound healing. However, the function of HO-1 in cutaneous inflammatory diseases, such as psoriasis, remains unknown. The abnormal activation of Stat3, a known tra...

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Detalles Bibliográficos
Autores principales: Zhang, Bin, Xie, Sijing, Su, Zhonglan, Song, Shiyu, Xu, Hui, Chen, Gang, Cao, Wangsen, Yin, Shasha, Gao, Qian, Wang, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759695/
https://www.ncbi.nlm.nih.gov/pubmed/26893174
http://dx.doi.org/10.1038/srep21132