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Quantitative prediction and clinical evaluation of an unexplored herb–drug interaction mechanism in healthy volunteers
Quantitative prediction of herb–drug interaction risk remains challenging. A quantitative framework to assess a potential interaction was used to evaluate a mechanism not previously tested in humans. The semipurified milk thistle product, silibinin, was selected as an exemplar herbal product inhibit...
Autores principales: | Gufford, BT, Barr, JT, González‐Pérez, V, Layton, ME, White, JR, Oberlies, NH, Paine, MF |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759704/ https://www.ncbi.nlm.nih.gov/pubmed/26904384 http://dx.doi.org/10.1002/psp4.12047 |
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