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An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients
BACKGROUND: Molecular characterization of circulating tumor cells (CTC) is promising for personalized medicine. We aimed to identify a CTC gene expression profile predicting outcome to first-line aromatase inhibitors in metastatic breast cancer (MBC) patients. Methods: CTCs were isolated from 78 MBC...
Autores principales: | Reijm, Esther A., Sieuwerts, Anieta M., Smid, Marcel, Vries, Joan Bolt-de, Mostert, Bianca, Onstenk, Wendy, Peeters, Dieter, Dirix, Luc Y., Seynaeve, Caroline M., Jager, Agnes, de Jongh, Felix E., Hamberg, Paul, van Galen, Anne, Kraan, Jaco, Jansen, Maurice P. H. M., Gratama, Jan W., Foekens, John A., Martens, John W. M., Berns, Els M. J. J., Sleijfer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759736/ https://www.ncbi.nlm.nih.gov/pubmed/26892682 http://dx.doi.org/10.1186/s12885-016-2155-y |
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