Transcriptomic analysis of the effects of Toll-like receptor 4 and its ligands on the gene expression network of hepatic stellate cells

BACKGROUND: Intact Toll-like receptor 4 (TLR4) has been identified in hepatic stellate cells (HSCs), the primary fibrogenic cell type in liver. Here, we investigated the impact of TLR4 signaling on the gene expression network of HSCs by comparing the transcriptomic changes between wild-type (JS1) an...

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Detalles Bibliográficos
Autores principales: Ouyang, Yangyang, Guo, Jinsheng, Lin, Chenzhao, Lin, Jie, Cao, Yirong, Zhang, Yuanqin, Wu, Yujin, Chen, Shiyao, Wang, Jiyao, Chen, Luonan, Friedman, Scott L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759739/
https://www.ncbi.nlm.nih.gov/pubmed/26900402
http://dx.doi.org/10.1186/s13069-016-0039-z

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