The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements

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Human CD4(+)CD25(hi)Foxp3(+)CD127(−) Treg and CD4(+)CD25(−)Foxp3(−) Tconv cell functions are governed by their metabolic requirements. Here we report a comprehensive comparative analysis between ex vivo human Treg and Tconv cells that comprises analyses of the proteomic networks in subcellular compa...

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Detalles Bibliográficos
Autores principales: Procaccini, Claudio, Carbone, Fortunata, Di Silvestre, Dario, Brambilla, Francesca, De Rosa, Veronica, Galgani, Mario, Faicchia, Deriggio, Marone, Gianni, Tramontano, Donatella, Corona, Marco, Alviggi, Carlo, Porcellini, Antonio, La Cava, Antonio, Mauri, Pierluigi, Matarese, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760097/
https://www.ncbi.nlm.nih.gov/pubmed/26885861
http://dx.doi.org/10.1016/j.immuni.2016.01.028
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