LLT1 and CD161 Expression in Human Germinal Centers Promotes B Cell Activation and CXCR4 Downregulation

Germinal centers (GCs) are microanatomical structures critical for the development of high-affinity Abs and B cell memory. They are organized into two zones, light and dark, with coordinated roles, controlled by local signaling. The innate lectin-like transcript 1 (LLT1) is known to be expressed on...

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Detalles Bibliográficos
Autores principales: Llibre, Alba, López-Macías, Constantino, Marafioti, Teresa, Mehta, Hema, Partridge, Amy, Kanzig, Carina, Rivellese, Felice, Galson, Jacob D., Walker, Lucy J., Milne, Paul, Phillips, Rodney E., Kelly, Dominic F., Freeman, Gordon J., El Shikh, Mohey Eldin, Klenerman, Paul, Willberg, Christian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Clinical and Human Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760235/
https://www.ncbi.nlm.nih.gov/pubmed/26829983
http://dx.doi.org/10.4049/jimmunol.1502462

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