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Co-delivery of PLGA encapsulated invariant NKT cell agonist with antigenic protein induce strong T cell-mediated antitumor immune responses
Antitumor immunity can be enhanced by the coordinated release and delivery of antigens and immune-stimulating agents to antigen-presenting cells via biodegradable vaccine carriers. So far, encapsulation of TLR ligands and tumor-associated antigens augmented cytotoxic T cell (CTLs) responses. Here, w...
Autores principales: | Dölen, Yusuf, Kreutz, Martin, Gileadi, Uzi, Tel, Jurjen, Vasaturo, Angela, van Dinther, Eric A. W., van Hout-Kuijer, Maaike A., Cerundolo, Vincenzo, Figdor, Carl G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760331/ https://www.ncbi.nlm.nih.gov/pubmed/26942088 http://dx.doi.org/10.1080/2162402X.2015.1068493 |
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