Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of MuSK myasthenia gravis

We investigated the influence of postsynaptic tyrosine kinase signaling in a mouse model of muscle‐specific kinase (MuSK) myasthenia gravis (MG). Mice administered repeated daily injections of IgG from MuSK MG patients developed impaired neuromuscular transmission due to progressive loss of acetylch...

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Detalles Bibliográficos
Autores principales: Ghazanfari, Nazanin, Linsao, Erna L. T. B., Trajanovska, Sofie, Morsch, Marco, Gregorevic, Paul, Liang, Simon X., Reddel, Stephen W., Phillips, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760443/
https://www.ncbi.nlm.nih.gov/pubmed/26702075
http://dx.doi.org/10.14814/phy2.12658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760443/
https://www.ncbi.nlm.nih.gov/pubmed/26702075
http://dx.doi.org/10.14814/phy2.12658

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