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Forced expression of muscle specific kinase slows postsynaptic acetylcholine receptor loss in a mouse model of MuSK myasthenia gravis
We investigated the influence of postsynaptic tyrosine kinase signaling in a mouse model of muscle‐specific kinase (MuSK) myasthenia gravis (MG). Mice administered repeated daily injections of IgG from MuSK MG patients developed impaired neuromuscular transmission due to progressive loss of acetylch...
Autores principales: | Ghazanfari, Nazanin, Linsao, Erna L. T. B., Trajanovska, Sofie, Morsch, Marco, Gregorevic, Paul, Liang, Simon X., Reddel, Stephen W., Phillips, William D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760443/ https://www.ncbi.nlm.nih.gov/pubmed/26702075 http://dx.doi.org/10.14814/phy2.12658 |
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