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Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis
Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease. Ureteric bud growth and branching requires GDNF signaling from the surrounding mesenchyme...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760680/ https://www.ncbi.nlm.nih.gov/pubmed/26894589 http://dx.doi.org/10.1371/journal.pbio.1002382 |