Ret and Etv4 Promote Directed Movements of Progenitor Cells during Renal Branching Morphogenesis

Branching morphogenesis of the epithelial ureteric bud forms the renal collecting duct system and is critical for normal nephron number, while low nephron number is implicated in hypertension and renal disease. Ureteric bud growth and branching requires GDNF signaling from the surrounding mesenchyme...

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Detalles Bibliográficos
Autores principales: Riccio, Paul, Cebrian, Cristina, Zong, Hui, Hippenmeyer, Simon, Costantini, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760680/
https://www.ncbi.nlm.nih.gov/pubmed/26894589
http://dx.doi.org/10.1371/journal.pbio.1002382

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