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Pimaradienoic Acid Inhibits Carrageenan-Induced Inflammatory Leukocyte Recruitment and Edema in Mice: Inhibition of Oxidative Stress, Nitric Oxide and Cytokine Production

Pimaradienoic acid (PA; ent-pimara-8(14),15-dien-19-oic acid) is a pimarane diterpene found in plants such as Vigueira arenaria Baker (Asteraceae) in the Brazilian savannas. Although there is evidence on the analgesic and in vitro inhibition of inflammatory signaling pathways, and paw edema by PA, i...

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Detalles Bibliográficos
Autores principales:	Mizokami, Sandra S., Hohmann, Miriam S. N., Staurengo-Ferrari, Larissa, Carvalho, Thacyana T., Zarpelon, Ana C., Possebon, Maria I., de Souza, Anderson R., Veneziani, Rodrigo C. S., Arakawa, Nilton S., Casagrande, Rubia, Verri, Waldiceu A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760730/ https://www.ncbi.nlm.nih.gov/pubmed/26895409 http://dx.doi.org/10.1371/journal.pone.0149656

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