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Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii

Toxoplasma gondii, a common brain-tropic parasite, is capable of infecting most nucleated cells, including astrocytes and neurons, in vitro. Yet, in vivo, Toxoplasma is primarily found in neurons. In vitro data showing that interferon-γ-stimulated astrocytes, but not neurons, clear intracellular par...

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Detalles Bibliográficos
Autores principales: Cabral, Carla M., Tuladhar, Shraddha, Dietrich, Hans K., Nguyen, Elizabeth, MacDonald, Wes R., Trivedi, Tapasya, Devineni, Asha, Koshy, Anita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760770/
https://www.ncbi.nlm.nih.gov/pubmed/26895155
http://dx.doi.org/10.1371/journal.ppat.1005447