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The Development of a Recombinant scFv Monoclonal Antibody Targeting Canine CD20 for Use in Comparative Medicine
Monoclonal antibodies are leading agents for therapeutic treatment of human diseases, but are limited in use by the paucity of clinically relevant models for validation. Sporadic canine tumours mimic the features of some human equivalents. Developing canine immunotherapeutics can be an approach for...
Autores principales: | Jain, Saurabh, Aresu, Luca, Comazzi, Stefano, Shi, Jianguo, Worrall, Erin, Clayton, John, Humphries, William, Hemmington, Sandra, Davis, Paul, Murray, Euan, Limeneh, Asmare A., Ball, Kathryn, Ruckova, Eva, Muller, Petr, Vojtesek, Borek, Fahraeus, Robin, Argyle, David, Hupp, Ted R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760772/ https://www.ncbi.nlm.nih.gov/pubmed/26894679 http://dx.doi.org/10.1371/journal.pone.0148366 |
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