Next-Generation Sequencing of a Single Domain Antibody Repertoire Reveals Quality of Phage Display Selected Candidates

Next-Generation Sequencing and bioinformatics are powerful tools for analyzing the large number of DNA sequences present in an immune library. In this work, we constructed a cDNA library of single domain antibodies from a llama immunized with staphylococcal enterotoxin B. The resulting library was s...

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Detalles Bibliográficos
Autores principales: Turner, Kendrick B., Naciri, Jennifer, Liu, Jinny L., Anderson, George P., Goldman, Ellen R., Zabetakis, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4760936/
https://www.ncbi.nlm.nih.gov/pubmed/26895405
http://dx.doi.org/10.1371/journal.pone.0149393

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