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Genetic analysis of intestinal polyp development in Collaborative Cross mice carrying the Apc(Min/+) mutation

BACKGROUND: Colorectal cancer is an abnormal tissue development in the colon or rectum. Most of CRCs develop due to somatic mutations, while only a small proportion is caused by inherited mutations. Familial adenomatous polyposis is an inherited genetic disease, which is characterized by colorectal...

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Detalles Bibliográficos
Autores principales:	Dorman, Alexandra, Baer, Daria, Tomlinson, Ian, Mott, Richard, Iraqi, Fuad A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761170/ https://www.ncbi.nlm.nih.gov/pubmed/26896154 http://dx.doi.org/10.1186/s12863-016-0349-6

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