Key role of MEK/ERK pathway in sustaining tumorigenicity and in vitro radioresistance of embryonal rhabdomyosarcoma stem-like cell population

BACKGROUND: The identification of signaling pathways that affect the cancer stem-like phenotype may provide insights into therapeutic targets for combating embryonal rhabdomyosarcoma. The aim of this study was to investigate the role of the MEK/ERK pathway in controlling the cancer stem-like phenoty...

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Detalles Bibliográficos
Autores principales: Ciccarelli, Carmela, Vulcano, Francesca, Milazzo, Luisa, Gravina, Giovanni Luca, Marampon, Francesco, Macioce, Giampiero, Giampaolo, Adele, Tombolini, Vincenzo, Di Paolo, Virginia, Hassan, Hamisa Jane, Zani, Bianca Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761200/
https://www.ncbi.nlm.nih.gov/pubmed/26897742
http://dx.doi.org/10.1186/s12943-016-0501-y

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