Cargando…
The trade-off of availability and growth inhibition through copper for the production of copper-dependent enzymes by Pichia pastoris
BACKGROUND: Copper is an essential chemical element for life as it is a part of prosthetic groups of enzymes including super oxide dismutase and cytochrome c oxidase; however, it is also toxic at high concentrations. Here, we present the trade-off of copper availability and growth inhibition of a co...
Autores principales: | Balakumaran, Palanisamy Athiyaman, Förster, Jan, Zimmermann, Martin, Charumathi, Jayachandran, Schmitz, Andreas, Czarnotta, Eik, Lehnen, Mathias, Sudarsan, Suresh, Ebert, Birgitta E., Blank, Lars Mathias, Meenakshisundaram, Sankaranarayanan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761204/ https://www.ncbi.nlm.nih.gov/pubmed/26897180 http://dx.doi.org/10.1186/s12896-016-0251-3 |
Ejemplares similares
-
Cofactor engineering improved CALB production in Pichia pastoris through heterologous expression of NADH oxidase and adenylate kinase
por: Jayachandran, Charumathi, et al.
Publicado: (2017) -
Improved microscale cultivation of Pichia pastoris for clonal screening
por: Eck, Alexander, et al.
Publicado: (2018) -
A comprehensive evaluation of constraining amino acid biosynthesis in compartmented models for metabolic flux analysis
por: Lehnen, Mathias, et al.
Publicado: (2017) -
Elevated temperatures do not trigger a conserved metabolic network response among thermotolerant yeasts
por: Lehnen, Mathias, et al.
Publicado: (2019) -
Predicting high recombinant protein producer strains of Pichia pastoris Mut(S) using the oxygen transfer rate as an indicator of metabolic burden
por: Wollborn, David, et al.
Publicado: (2022)