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Mechanistic Models Predict Efficacy of CCR5‐Deficient Stem Cell Transplants in HIV Patient Populations

Combination antiretroviral therapy (cART) effectively suppresses viral load in HIV‐infected individuals, but it is not a cure. Bone marrow transplants using HIV‐resistant stem cells have renewed hope that cure is achievable but key questions remain e.g., what percentage of stem cells must be HIV‐res...

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Detalles Bibliográficos
Autores principales: Hosseini, I, Gabhann, F Mac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761230/
https://www.ncbi.nlm.nih.gov/pubmed/26933519
http://dx.doi.org/10.1002/psp4.12059