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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential

Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite involved in many critical cell processes. It is produced by the phosphorylation of sphingosine by sphingosine kinases (SphKs) and exported out of cells via transporters such as spinster homolog 2 (Spns2). S1P regulates diverse phys...

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Detalles Bibliográficos
Autores principales:	Aoki, Masayo, Aoki, Hiroaki, Ramanathan, Rajesh, Hait, Nitai C., Takabe, Kazuaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761394/ https://www.ncbi.nlm.nih.gov/pubmed/26966342 http://dx.doi.org/10.1155/2016/8606878

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