Cargando…

Innervation of Cochlear Hair Cells by Human Induced Pluripotent Stem Cell-Derived Neurons In Vitro

Induced pluripotent stem cells (iPSCs) may serve as an autologous source of replacement neurons in the injured cochlea, if they can be successfully differentiated and reconnected with residual elements in the damaged auditory system. Here, we explored the potential of hiPSC-derived neurons to innerv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gunewardene, Niliksha, Crombie, Duncan, Dottori, Mirella, Nayagam, Bryony A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761396/ https://www.ncbi.nlm.nih.gov/pubmed/26966437 http://dx.doi.org/10.1155/2016/1781202

Ejemplares similares

Directing Human Induced Pluripotent Stem Cells into a Neurosensory Lineage for Auditory Neuron Replacement
por: Gunewardene, Niliksha, et al.
Publicado: (2014)

Organotypic Cocultures of Human Pluripotent Stem Cell Derived-Neurons with Mammalian Inner Ear Hair Cells and Cochlear Nucleus Slices
por: Hyakumura, Tomoko, et al.
Publicado: (2019)

Applications of Lgr5-Positive Cochlear Progenitors (LCPs) to the Study of Hair Cell Differentiation
por: Lenz, Danielle R., et al.
Publicado: (2019)

Generation of Neural Organoids from Human Embryonic Stem Cells Using the Rotary Cell Culture System: Effects of Microgravity on Neural Progenitor Cell Fate
por: Mattei, Cristiana, et al.
Publicado: (2018)

Generation of Vestibular Tissue-Like Organoids From Human Pluripotent Stem Cells Using the Rotary Cell Culture System
por: Mattei, Cristiana, et al.
Publicado: (2019)

Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells
por: Alshawaf, Abdullah Jawad, et al.
Publicado: (2018)

Editorial: Reviews in induced pluripotent stem cells
por: Dottori, Mirella, et al.
Publicado: (2023)

Unrestricted somatic stem cells from human umbilical cord blood grow in serum-free medium as spheres
por: Zaibak, Faten, et al.
Publicado: (2009)

Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells
por: Ceriani, Federico, et al.
Publicado: (2019)

Ouabain-Induced Apoptosis in Cochlear Hair Cells and Spiral Ganglion Neurons In Vitro
por: Fu, Yong, et al.
Publicado: (2013)

Stem Cells as In Vitro Models of Disease
por: Dottori, Mirella, et al.
Publicado: (2012)

Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells
por: Abu-Bonsrah, Kwaku Dad, et al.
Publicado: (2017)

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
por: Jeong, Minjin, et al.
Publicado: (2018)

WDR62 Regulates Early Neural and Glial Progenitor Specification of Human Pluripotent Stem Cells
por: Alshawaf, Abdullah J., et al.
Publicado: (2017)

Long‐Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived from Human Induced Pluripotent Stem Cells After Intracerebral Transplantation
por: Niclis, Jonathan C., et al.
Publicado: (2017)

Neuronal differentiation of hair-follicle-bulge-derived stem cells co-cultured with mouse cochlear modiolus explants
por: Schomann, Timo, et al.
Publicado: (2017)

Friedreich's ataxia induced pluripotent stem cell-derived cardiomyocytes display electrophysiological abnormalities and calcium handling deficiency
por: Crombie, Duncan E., et al.
Publicado: (2017)

Derivation of Hair-Inducing Cell from Human Pluripotent Stem Cells
por: Gnedeva, Ksenia, et al.
Publicado: (2015)

Engineering human skin model innervated with itch sensory neuron‐like cells differentiated from induced pluripotent stem cells
por: Guo, Zongyou, et al.
Publicado: (2021)

Graphene foam as a biocompatible scaffold for culturing human neurons
por: D'Abaco, Giovanna M., et al.
Publicado: (2018)

Human stem cells ameliorate auditory evoked responses in a model of neuropathy
por: Nayagam, Bryony Ariya
Publicado: (2012)

Development of Functional Thyroid C Cell-like Cells from Human Pluripotent Cells in 2D and in 3D Scaffolds
por: Abu-Bonsrah, Kwaku Dad, et al.
Publicado: (2021)

Cochlear hair cell densities in the rabbit
por: Yuan, Fang, et al.
Publicado: (2018)

Developmental expression of BK channels in chick cochlear hair cells
por: Li, Yi, et al.
Publicado: (2009)

Enriched retinal ganglion cells derived from human embryonic stem cells
por: Gill, Katherine P., et al.
Publicado: (2016)

Viral-mediated transduction of auditory neurons with opsins for optical and hybrid activation
por: Richardson, Rachael T., et al.
Publicado: (2021)

Facioscapulohumeral dystrophy weakened sarcomeric contractility is mimicked in induced pluripotent stem cells‐derived innervated muscle fibres
por: Laberthonnière, Camille, et al.
Publicado: (2021)

Characterization of forebrain neurons derived from late-onset Huntington's disease human embryonic stem cell lines
por: Niclis, Jonathan C., et al.
Publicado: (2013)

Induced pluripotent stem cells from human hair follicle keratinocytes as a potential source for in vitro hair follicle cloning
por: Lim, Sheng Jye, et al.
Publicado: (2016)

Functional assembly of mammalian cochlear hair cells
por: Marcotti, Walter
Publicado: (2012)

The cochlear outer hair cell speed paradox
por: Rabbitt, Richard D.
Publicado: (2020)

Induced Pluripotent Stem Cells from Human Hair Follicle Mesenchymal Stem Cells
por: Wang, Yimei, et al.
Publicado: (2012)

Functional Characterization of Friedreich Ataxia iPS-Derived Neuronal Progenitors and Their Integration in the Adult Brain
por: Bird, Matthew J., et al.
Publicado: (2014)

Deletion of Clusterin Protects Cochlear Hair Cells against Hair Cell Aging and Ototoxicity
por: Zhao, Xiaochang, et al.
Publicado: (2021)

Regenerated hair cells in the neonatal cochlea are innervated and the majority co-express markers of both inner and outer hair cells
por: Heuermann, Mitchell L., et al.
Publicado: (2022)

The neural milieu of the developing choroid plexus: neural stem cells, neurons and innervation
por: Prasongchean, Weerapong, et al.
Publicado: (2015)

Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons
por: Coate, Thomas M, et al.
Publicado: (2015)

Modulatory Role of Sensory Innervation on Hair Follicle Stem Cell Progeny during Wound Healing of the Rat Skin
por: Martínez-Martínez, Eduardo, et al.
Publicado: (2012)

Electrophysiological property and chemical sensitivity of primary afferent neurons that innervate rat whisker hair follicles
por: Ikeda, Ryo, et al.
Publicado: (2016)

Spatial distribution of neurons innervated by chandelier cells
por: Blazquez-Llorca, Lidia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_2tc8jjqqveij9sab6g51n1e9mu