Uncoupling Protein 2 Increases Susceptibility to Lipopolysaccharide-Induced Acute Lung Injury in Mice

Uncoupling protein 2 (UCP2) is upregulated in patients with systemic inflammation and infection, but its functional role is unclear. We up- or downregulated UCP2 expression using UCP2 recombinant adenovirus or the UCP2 inhibitor, genipin, in lungs of mice, and investigated the mechanisms of UCP2 in...

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Detalles Bibliográficos
Autores principales: Wang, Qin, Wang, Jianchun, Hu, Mingdong, Yang, Yu, Guo, Liang, Xu, Jing, Lei, Chuanjiang, Jiao, Yan, Xu, JianCheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761398/
https://www.ncbi.nlm.nih.gov/pubmed/27057102
http://dx.doi.org/10.1155/2016/9154230

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