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Mechanical response of cardiovascular stents under vascular dynamic bending

BACKROUND: Currently, the effect of vascular dynamic bending (VDB) has not been fully considered when studying cardiovascular stents’ long-term mechanical properties, as the previous studies about stent’s mechanical properties mostly focus on the effect of vascular pulsation (VP). More and more clin...

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Autores principales: Xu, Jiang, Yang, Jie, Huang, Nan, Uhl, Christopher, Zhou, Yihua, Liu, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761418/
https://www.ncbi.nlm.nih.gov/pubmed/26897123
http://dx.doi.org/10.1186/s12938-016-0135-8
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author Xu, Jiang
Yang, Jie
Huang, Nan
Uhl, Christopher
Zhou, Yihua
Liu, Yaling
author_facet Xu, Jiang
Yang, Jie
Huang, Nan
Uhl, Christopher
Zhou, Yihua
Liu, Yaling
author_sort Xu, Jiang
collection PubMed
description BACKROUND: Currently, the effect of vascular dynamic bending (VDB) has not been fully considered when studying cardiovascular stents’ long-term mechanical properties, as the previous studies about stent’s mechanical properties mostly focus on the effect of vascular pulsation (VP). More and more clinical reports suggested that the effect of VDB have a significant impact on stent. METHODS: In this paper, an explicit-implicit coupling simulation method was applied to analyze the mechanical responses of cardiovascular stents considering the effect of VDB. The effect of VP on stent mechanical properties was also studied and compared to the effect of VDB. RESULTS: The results showed that the dynamic bending deformation occurred in stents due to the effect of VDB. The effects of VDB and VP resulted in alternating stress states of the stent, while the VDB alternate stresses effective on the stent were almost three times larger than that of the VP. The stress concentration under VDB mainly occurred in bridge struts and the maximal stress was located in the middle loops of the stent. However, the stress distributed uniformly in the stents under the effect of VP. Stent fracture occurred more frequently as a result of VDB with the predicted fracture position located in the bridging struts of the stent. These results are consistent with the reported data in clinical literatures. The stress of the vessel under VDB was higher, than that caused by VP. CONCLUSIONS: The results showed that the effect of VDB has a significant impact on the stent’s stress distribution, fatigue performance and overall stress on the vessel, thus it is necessary to be considered when analyzing stent’s long-term mechanical properties. Meanwhile, the results showed that the explicit-implicit coupling simulation can be applied to analyze stent mechanical properties.
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spelling pubmed-47614182016-02-22 Mechanical response of cardiovascular stents under vascular dynamic bending Xu, Jiang Yang, Jie Huang, Nan Uhl, Christopher Zhou, Yihua Liu, Yaling Biomed Eng Online Research BACKROUND: Currently, the effect of vascular dynamic bending (VDB) has not been fully considered when studying cardiovascular stents’ long-term mechanical properties, as the previous studies about stent’s mechanical properties mostly focus on the effect of vascular pulsation (VP). More and more clinical reports suggested that the effect of VDB have a significant impact on stent. METHODS: In this paper, an explicit-implicit coupling simulation method was applied to analyze the mechanical responses of cardiovascular stents considering the effect of VDB. The effect of VP on stent mechanical properties was also studied and compared to the effect of VDB. RESULTS: The results showed that the dynamic bending deformation occurred in stents due to the effect of VDB. The effects of VDB and VP resulted in alternating stress states of the stent, while the VDB alternate stresses effective on the stent were almost three times larger than that of the VP. The stress concentration under VDB mainly occurred in bridge struts and the maximal stress was located in the middle loops of the stent. However, the stress distributed uniformly in the stents under the effect of VP. Stent fracture occurred more frequently as a result of VDB with the predicted fracture position located in the bridging struts of the stent. These results are consistent with the reported data in clinical literatures. The stress of the vessel under VDB was higher, than that caused by VP. CONCLUSIONS: The results showed that the effect of VDB has a significant impact on the stent’s stress distribution, fatigue performance and overall stress on the vessel, thus it is necessary to be considered when analyzing stent’s long-term mechanical properties. Meanwhile, the results showed that the explicit-implicit coupling simulation can be applied to analyze stent mechanical properties. BioMed Central 2016-02-20 /pmc/articles/PMC4761418/ /pubmed/26897123 http://dx.doi.org/10.1186/s12938-016-0135-8 Text en © Xu et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Xu, Jiang
Yang, Jie
Huang, Nan
Uhl, Christopher
Zhou, Yihua
Liu, Yaling
Mechanical response of cardiovascular stents under vascular dynamic bending
title Mechanical response of cardiovascular stents under vascular dynamic bending
title_full Mechanical response of cardiovascular stents under vascular dynamic bending
title_fullStr Mechanical response of cardiovascular stents under vascular dynamic bending
title_full_unstemmed Mechanical response of cardiovascular stents under vascular dynamic bending
title_short Mechanical response of cardiovascular stents under vascular dynamic bending
title_sort mechanical response of cardiovascular stents under vascular dynamic bending
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761418/
https://www.ncbi.nlm.nih.gov/pubmed/26897123
http://dx.doi.org/10.1186/s12938-016-0135-8
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