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Threonine aldolases: perspectives in engineering and screening the enzymes with enhanced substrate and stereo specificities
Threonine aldolases have emerged as a powerful tool for asymmetric carbon-carbon bond formation. These enzymes catalyse the unnatural aldol condensation of different aldehydes and glycine to produce highly valuable β-hydroxy-α-amino acids with complete stereocontrol at the α-carbon and moderate spec...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761611/ https://www.ncbi.nlm.nih.gov/pubmed/26810201 http://dx.doi.org/10.1007/s00253-015-7218-5 |