Cargando…

Challenging Treatment-Resistant Major Depressive Disorder: A Roadmap for Improved Therapeutics

Major depressive disorder (MDD) is associated with a significant burden and costs to the society. As remission of depressive symptoms is achieved in only one-third of the MDD patients after the first antidepressant trial, unsuccessful treatments contribute largely to the observed suffering and socia...

Descripción completa

Detalles Bibliográficos
Autores principales:	de Sousa, Rafael T., Zanetti, Marcus V., Brunoni, Andre R., Machado-Vieira, Rodrigo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761633/ https://www.ncbi.nlm.nih.gov/pubmed/26467411 http://dx.doi.org/10.2174/1570159X13666150630173522

Ejemplares similares

Therapeutic Modulation of Glutamate Receptors in Major Depressive Disorder
por: Jaso, Brittany A., et al.
Publicado: (2017)

Temperament and character traits in major depressive disorder: a case control study
por: Nogueira, Barbara Schwair, et al.
Publicado: (2017)

Experimental Therapeutics in Treatment-Resistant Major Depressive Disorder
por: Kaur, Mandeep, et al.
Publicado: (2021)

Distorted thoughts as a mediator of depressive symptoms in patients with major depressive disorder: a longitudinal study
por: Carneiro, Adriana Munhoz, et al.
Publicado: (2023)

CTA Challenges and Roadmap
por: Davis, Michael
Publicado: (2023)

Neuroanatomical Classification in a Population-Based Sample of Psychotic Major Depression and Bipolar I Disorder with 1 Year of Diagnostic Stability
por: Serpa, Mauricio H., et al.
Publicado: (2014)

Intermittent Fasting as a Potential Therapeutic Instrument for Major Depression Disorder: A Systematic Review of Clinical and Preclinical Studies
por: Murta, Laís, et al.
Publicado: (2023)

Acute Ketamine Administration Corrects Abnormal Inflammatory Bone Markers in Major Depressive Disorder
por: Kadriu, Bashkim, et al.
Publicado: (2017)

Predicting treatment response using EEG in major depressive disorder: A machine-learning meta-analysis
por: Watts, Devon, et al.
Publicado: (2022)

Bimodal Effect of Lithium Plasma Levels on Hippocampal Glutamate Concentrations in Bipolar II Depression: A Pilot Study
por: Zanetti, Marcus V., et al.
Publicado: (2015)

Atypical Antipsychotics and Other Therapeutic Options for Treatment of Resistant Major Depressive Disorder
por: Seo, Rubo J., et al.
Publicado: (2010)

A Systematic Review of Non-Invasive Brain Stimulation Therapies and Cardiovascular Risk: Implications for the Treatment of Major Depressive Disorder
por: Sampaio, Leonardo Augusto Negreiros Parente Capela, et al.
Publicado: (2012)

Lithium efficacy in bipolar depression with flexible dosing: A six-week, open-label, proof-of-concept study
por: MACHADO-VIEIRA, RODRIGO, et al.
Publicado: (2014)

Adjunctive transcranial alternating current stimulation for patients with major depressive disorder: A systematic review and meta-analysis
por: Zheng, Wei, et al.
Publicado: (2023)

Major depressive disorder: Validated treatments and future challenges
por: Karrouri, Rabie, et al.
Publicado: (2021)

Placebo Response of Non-Pharmacological and Pharmacological Trials in Major Depression: A Systematic Review and Meta-Analysis
por: Brunoni, André Russowsky, et al.
Publicado: (2009)

Probiotics as a therapeutic strategy in Major Depressive Disorder
por: Vargas, L.
Publicado: (2022)

Forecasting major impacts of COVID-19 pandemic on country-driven sectors: challenges, lessons, and future roadmap
por: Kumar, Saket, et al.
Publicado: (2021)

Atopic Dermatitis and Major Depressive Disorder: is there causality?
por: Reis, C. S., et al.
Publicado: (2023)

Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder
por: Rong, Carola, et al.
Publicado: (2018)

Predictors of Major Depressive Disorder in Older People
por: Sousa, Susana, et al.
Publicado: (2021)

Progress and challenges in research of the mechanisms of anhedonia in major depressive disorder
por: Su, Yun-Ai, et al.
Publicado: (2022)

The EHA Research Roadmap: Platelet Disorders
por: Balduini, Carlo, et al.
Publicado: (2021)

Suicide‐specific mortality among patients with treatment‐resistant major depressive disorder, major depressive disorder with prior suicidal ideation or suicide attempts, or major depressive disorder alone
por: Kern, David M., et al.
Publicado: (2023)

Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
por: Han, Laura K. M., et al.
Publicado: (2020)

Antidepressant Efficacy of Adjunctive Aerobic Activity and Associated Biomarkers in Major Depression: A 4-Week, Randomized, Single-Blind, Controlled Clinical Trial
por: Siqueira, Cristiana Carvalho, et al.
Publicado: (2016)

Roadmap for Stroke: Challenging the Role of the Neuronal Extracellular Matrix
por: De Luca, Ciro, et al.
Publicado: (2020)

The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase
por: Pereira Junior, Bernardo de Sampaio, et al.
Publicado: (2015)

DNA Methylation as a Therapeutic and Diagnostic Target in Major Depressive Disorder
por: Lax, Elad
Publicado: (2022)

Epidemiology of treatment resistant depression among major depressive disorder patients in Israel
por: Sharman Moser, Sarah, et al.
Publicado: (2022)

6-Sulfatoxymelatonin predicts treatment response to fluoxetine in major depressive disorder
por: Jury Freitas, Juliana, et al.
Publicado: (2019)

Roadmap toward the 10 ps time-of-flight PET challenge
por: Lecoq, Paul, et al.
Publicado: (2020)

In-Time Explainability in Multi-Agent Systems: Challenges, Opportunities, and Roadmap
por: Alzetta, Francesco, et al.
Publicado: (2020)

Treatment strategies to improve and sustain remission in major depressive disorder
por: Madhukar H., Trivedi, et al.
Publicado: (2008)

Selegiline remarkably improved stage 5 treatment-resistant major depressive disorder: a case report
por: Kitaichi, Yuji, et al.
Publicado: (2013)

The EHA Research Roadmap: Blood Coagulation and Hemostatic Disorders
por: Eichinger, Sabine, et al.
Publicado: (2021)

Challenges in the development of clinical trials for major depressive disorder: lessons learned from trials in minor depression
por: Rapaport, Mark H., et al.
Publicado: (2002)

Changes in insulin resistance following antidepressant treatment mediate response in major depressive disorder
por: Rashidian, Houman, et al.
Publicado: (2022)

Treatment-resistant depression: therapeutic trends, challenges, and future directions
por: Al-Harbi, Khalid Saad
Publicado: (2012)

Emerging role of microRNAs in major depressive disorder: diagnosis and therapeutic implications
por: Dwivedi, Yogesh
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_k5meldj0cjrc0j4rc4k1dhk9nm