Nutrition and lifestyle in healthy aging: the telomerase challenge

Nutrition and lifestyle, known to modulate aging process and age-related diseases, might also affect telomerase activity. Short and dysfunctional telomeres rather than average telomere length are associated with longevity in animal models, and their rescue by telomerase maybe sufficient to restore c...

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Detalles Bibliográficos
Autores principales: Boccardi, Virginia, Paolisso, Giuseppe, Mecocci, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761710/
https://www.ncbi.nlm.nih.gov/pubmed/26826704
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author Boccardi, Virginia
Paolisso, Giuseppe
Mecocci, Patrizia
author_facet Boccardi, Virginia
Paolisso, Giuseppe
Mecocci, Patrizia
author_sort Boccardi, Virginia
collection PubMed
description Nutrition and lifestyle, known to modulate aging process and age-related diseases, might also affect telomerase activity. Short and dysfunctional telomeres rather than average telomere length are associated with longevity in animal models, and their rescue by telomerase maybe sufficient to restore cell and organismal viability. Improving telomerase activation in stem cells and potentially in other cells by diet and lifestyle interventions may represent an intriguing way to promote health-span in humans.
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spelling pubmed-47617102016-03-11 Nutrition and lifestyle in healthy aging: the telomerase challenge Boccardi, Virginia Paolisso, Giuseppe Mecocci, Patrizia Aging (Albany NY) Research Perspective Nutrition and lifestyle, known to modulate aging process and age-related diseases, might also affect telomerase activity. Short and dysfunctional telomeres rather than average telomere length are associated with longevity in animal models, and their rescue by telomerase maybe sufficient to restore cell and organismal viability. Improving telomerase activation in stem cells and potentially in other cells by diet and lifestyle interventions may represent an intriguing way to promote health-span in humans. Impact Journals LLC 2016-01-30 /pmc/articles/PMC4761710/ /pubmed/26826704 Text en Copyright: © 2016 Boccardi et al. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Perspective
Boccardi, Virginia
Paolisso, Giuseppe
Mecocci, Patrizia
Nutrition and lifestyle in healthy aging: the telomerase challenge
title Nutrition and lifestyle in healthy aging: the telomerase challenge
title_full Nutrition and lifestyle in healthy aging: the telomerase challenge
title_fullStr Nutrition and lifestyle in healthy aging: the telomerase challenge
title_full_unstemmed Nutrition and lifestyle in healthy aging: the telomerase challenge
title_short Nutrition and lifestyle in healthy aging: the telomerase challenge
title_sort nutrition and lifestyle in healthy aging: the telomerase challenge
topic Research Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761710/
https://www.ncbi.nlm.nih.gov/pubmed/26826704
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