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Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance

Accumulated studies demonstrate that saturated fatty acids (FAs) such as palmitic acid (PA) inhibit insulin signaling in skeletal muscle cells and monounsaturated fatty acids such as oleic acid (OA) reverse the effect of PA on insulin signaling. The detailed molecular mechanism of these opposite eff...

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Detalles Bibliográficos
Autores principales: Chen, Xiulan, Xu, Shimeng, Wei, Shasha, Deng, Yaqin, Li, Yiran, Yang, Fuquan, Liu, Pingsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761885/
https://www.ncbi.nlm.nih.gov/pubmed/26899878
http://dx.doi.org/10.1038/srep21454

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