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Comparative Proteomic Study of Fatty Acid-treated Myoblasts Reveals Role of Cox-2 in Palmitate-induced Insulin Resistance
Accumulated studies demonstrate that saturated fatty acids (FAs) such as palmitic acid (PA) inhibit insulin signaling in skeletal muscle cells and monounsaturated fatty acids such as oleic acid (OA) reverse the effect of PA on insulin signaling. The detailed molecular mechanism of these opposite eff...
Autores principales: | Chen, Xiulan, Xu, Shimeng, Wei, Shasha, Deng, Yaqin, Li, Yiran, Yang, Fuquan, Liu, Pingsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761885/ https://www.ncbi.nlm.nih.gov/pubmed/26899878 http://dx.doi.org/10.1038/srep21454 |
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