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Transport of pyruvate into mitochondria is involved in methylmercury toxicity
We have previously demonstrated that the overexpression of enzymes involved in the production of pyruvate, enolase 2 (Eno2) and D-lactate dehydrogenase (Dld3) renders yeast highly sensitive to methylmercury and that the promotion of intracellular pyruvate synthesis may be involved in intensifying th...
Autores principales: | Lee, Jin-Yong, Ishida, Yosuke, Takahashi, Tsutomu, Naganuma, Akira, Hwang, Gi-Wook |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761912/ https://www.ncbi.nlm.nih.gov/pubmed/26899208 http://dx.doi.org/10.1038/srep21528 |
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