A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment

MicroRNAs (miRs) play pivotal roles in carcinogenesis and endoplasmic reticulum (ER) that performs the folding, modification and trafficking of proteins targeted to the secretory pathway. Cancer cells often endure ER stress during tumor progression but use the adaptive ER stress response to gain sur...

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Detalles Bibliográficos
Autores principales: Jiang, Lili, Zang, Dan, Yi, Songgang, Li, Xiaofen, Yang, Changshan, Dong, Xiaoxian, Zhao, Chong, Lan, Xiaoying, Chen, Xin, Liu, Shouting, Liu, Ningning, Huang, Hongbiao, Shi, Xianping, Wang, Xuejun, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761930/
https://www.ncbi.nlm.nih.gov/pubmed/26898246
http://dx.doi.org/10.1038/srep21565

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