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GATA3 inhibits GCM1 activity and trophoblast cell invasion

Development of human placenta involves the invasion of trophoblast cells from anchoring villi into the maternal decidua. Placental transcription factor GCM1 regulates trophoblast cell invasion via transcriptional activation of HtrA4 gene, which encodes a serine protease enzyme. The GATA3 transcripti...

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Detalles Bibliográficos
Autores principales: Chiu, Yueh Ho, Chen, Hungwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761948/
https://www.ncbi.nlm.nih.gov/pubmed/26899996
http://dx.doi.org/10.1038/srep21630