In silico selection of an aptamer to estrogen receptor alpha using computational docking employing estrogen response elements as aptamer-alike molecules

Aptamers, the chemical-antibody substitute to conventional antibodies, are primarily discovered through SELEX technology involving multi-round selections and enrichment. Circumventing conventional methodology, here we report an in silico selection of aptamers to estrogen receptor alpha (ERα) using R...

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Detalles Bibliográficos
Autores principales: Ahirwar, Rajesh, Nahar, Smita, Aggarwal, Shikha, Ramachandran, Srinivasan, Maiti, Souvik, Nahar, Pradip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761961/
https://www.ncbi.nlm.nih.gov/pubmed/26899418
http://dx.doi.org/10.1038/srep21285

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