Detection and delineation of oral cancer with a PARP1 targeted optical imaging agent

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Earlier and more accurate detection of oral squamous cell carcinoma (OSCC) is essential to improve the prognosis of patients and to reduce the morbidity of surgical therapy. Here, we demonstrate that the nuclear enzyme Poly(ADP-ribose)Polymerase 1 (PARP1) is a promising target for optical imaging of...

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Detalles Bibliográficos
Autores principales: Kossatz, Susanne, Brand, Christian, Gutiontov, Stanley, Liu, Jonathan T. C., Lee, Nancy Y., Gönen, Mithat, Weber, Wolfgang A., Reiner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761964/
https://www.ncbi.nlm.nih.gov/pubmed/26900125
http://dx.doi.org/10.1038/srep21371

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