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ERK and AKT phosphorylation status in lung cancer and emphysema using nanocapillary isoelectric focusing

BACKGROUND: Emphysema is an independent risk factor for the development of lung cancer in smokers. Activation of oncogenic signalling proteins AKT and ERK by phosphorylation has an established role in the development of lung cancer and has also been implicated in the pathogenesis of emphysema. The a...

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Detalles Bibliográficos
Autores principales: Crosbie, Philip A J, Crosbie, Emma J, Aspinall-O'Dea, Mark, Walker, Michael, Harrison, Rebecca, Pernemalm, Maria, Shah, Rajesh, Joseph, Leena, Booton, Richard, Pierce, Andrew, Whetton, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762086/
https://www.ncbi.nlm.nih.gov/pubmed/26918193
http://dx.doi.org/10.1136/bmjresp-2015-000114