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Methods of a large prospective, randomised, open-label, blinded end-point study comparing morning versus evening dosing in hypertensive patients: the Treatment In Morning versus Evening (TIME) study

INTRODUCTION: Nocturnal blood pressure (BP) appears to be a better predictor of cardiovascular outcome than daytime BP. The BP lowering effects of most antihypertensive therapies are often greater in the first 12 h compared to the next 12 h. The Treatment In Morning versus Evening (TIME) study aims...

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Detalles Bibliográficos
Autores principales: Rorie, David A, Rogers, Amy, Mackenzie, Isla S, Ford, Ian, Webb, David J, Willams, Bryan, Brown, Morris, Poulter, Neil, Findlay, Evelyn, Saywood, Wendy, MacDonald, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762112/
https://www.ncbi.nlm.nih.gov/pubmed/26861939
http://dx.doi.org/10.1136/bmjopen-2015-010313