A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example

The prevalence of chronic viral infectious diseases, the emergence and re-emergence of new viral infections, and in particular, resistance to currently used antiviral drugs have led to increased demand for new antiviral strategies and reagents. Increased understanding of the molecular mechanisms of...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Lin, Zhu, Shouhai, Wang, Yaxin, Lou, Zhiyong, Sun, Yuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762143/
https://www.ncbi.nlm.nih.gov/pubmed/26942222
http://dx.doi.org/10.1007/s41048-015-0006-z
_version_ 1782417067812585472
author Cao, Lin
Zhu, Shouhai
Wang, Yaxin
Lou, Zhiyong
Sun, Yuna
author_facet Cao, Lin
Zhu, Shouhai
Wang, Yaxin
Lou, Zhiyong
Sun, Yuna
author_sort Cao, Lin
collection PubMed
description The prevalence of chronic viral infectious diseases, the emergence and re-emergence of new viral infections, and in particular, resistance to currently used antiviral drugs have led to increased demand for new antiviral strategies and reagents. Increased understanding of the molecular mechanisms of viral infection has provided great potential for the discovery of new antiviral agents that target viral proteins or host factors. In this work, we introduce a comprehensive system using enteroviruses 71 (EV71) as an example for leading compound discovery to develop new antiviral.
format Online
Article
Text
id pubmed-4762143
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Springer Berlin Heidelberg
record_format MEDLINE/PubMed
spelling pubmed-47621432016-03-01 A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example Cao, Lin Zhu, Shouhai Wang, Yaxin Lou, Zhiyong Sun, Yuna Biophys Rep Methods The prevalence of chronic viral infectious diseases, the emergence and re-emergence of new viral infections, and in particular, resistance to currently used antiviral drugs have led to increased demand for new antiviral strategies and reagents. Increased understanding of the molecular mechanisms of viral infection has provided great potential for the discovery of new antiviral agents that target viral proteins or host factors. In this work, we introduce a comprehensive system using enteroviruses 71 (EV71) as an example for leading compound discovery to develop new antiviral. Springer Berlin Heidelberg 2015-08-22 2015 /pmc/articles/PMC4762143/ /pubmed/26942222 http://dx.doi.org/10.1007/s41048-015-0006-z Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Methods
Cao, Lin
Zhu, Shouhai
Wang, Yaxin
Lou, Zhiyong
Sun, Yuna
A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title_full A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title_fullStr A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title_full_unstemmed A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title_short A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example
title_sort comprehensive procedure for antiviral inhibitor discovery using ev71 as an example
topic Methods
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762143/
https://www.ncbi.nlm.nih.gov/pubmed/26942222
http://dx.doi.org/10.1007/s41048-015-0006-z
work_keys_str_mv AT caolin acomprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT zhushouhai acomprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT wangyaxin acomprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT louzhiyong acomprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT sunyuna acomprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT caolin comprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT zhushouhai comprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT wangyaxin comprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT louzhiyong comprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample
AT sunyuna comprehensiveprocedureforantiviralinhibitordiscoveryusingev71asanexample

Ejemplares similares