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A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism

The Mediator complex governs gene expression by linking upstream signaling pathways with the basal transcriptional machinery. However, how individual Mediator subunits may function in different tissues remains to be investigated. Through skeletal muscle-specific deletion of the Mediator subunit MED1...

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Detalles Bibliográficos
Autores principales: Amoasii, Leonela, Holland, William, Sanchez-Ortiz, Efrain, Baskin, Kedryn K., Pearson, Mackenzie, Burgess, Shawn C., Nelson, Benjamin R., Bassel-Duby, Rhonda, Olson, Eric N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762428/
https://www.ncbi.nlm.nih.gov/pubmed/26883362
http://dx.doi.org/10.1101/gad.273128.115

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