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A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism
The Mediator complex governs gene expression by linking upstream signaling pathways with the basal transcriptional machinery. However, how individual Mediator subunits may function in different tissues remains to be investigated. Through skeletal muscle-specific deletion of the Mediator subunit MED1...
Autores principales: | Amoasii, Leonela, Holland, William, Sanchez-Ortiz, Efrain, Baskin, Kedryn K., Pearson, Mackenzie, Burgess, Shawn C., Nelson, Benjamin R., Bassel-Duby, Rhonda, Olson, Eric N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762428/ https://www.ncbi.nlm.nih.gov/pubmed/26883362 http://dx.doi.org/10.1101/gad.273128.115 |
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