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Pharmacodynamic Biomarker Development for PI3K Pathway Therapeutics
The phosphatidylinositol 3-kinase (PI3K) signaling pathway is integral to many essential cell processes, including cell growth, differentiation, proliferation, motility, and metabolism. Somatic mutations and genetic amplifications that result in activation of the pathway are frequently detected in c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762492/ https://www.ncbi.nlm.nih.gov/pubmed/26917948 http://dx.doi.org/10.4137/TOG.S30529 |