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Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery

OBJECTIVE: To test several weaning predictors as determinants of successful extubation after elective cardiac surgery. METHODS: The study was conducted at a tertiary hospital with 100 adult patients undergoing elective cardiac surgery from September to December 2014. We recorded demographic, clinica...

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Autores principales: Silva, Mayara Gabrielle Barbosa e, Borges, Daniel Lago, Costa, Marina de Albuquerque Gonçalves, Baldez, Thiago Eduardo Pereira, da Silva, Luan Nascimento, Oliveira, Rafaella Lima, Ferreira, Teresa de Fátima Ramos, Albuquerque, Renato Adams Matos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762550/
https://www.ncbi.nlm.nih.gov/pubmed/26934398
http://dx.doi.org/10.5935/1678-9741.20150076
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author Silva, Mayara Gabrielle Barbosa e
Borges, Daniel Lago
Costa, Marina de Albuquerque Gonçalves
Baldez, Thiago Eduardo Pereira
da Silva, Luan Nascimento
Oliveira, Rafaella Lima
Ferreira, Teresa de Fátima Ramos
Albuquerque, Renato Adams Matos
author_facet Silva, Mayara Gabrielle Barbosa e
Borges, Daniel Lago
Costa, Marina de Albuquerque Gonçalves
Baldez, Thiago Eduardo Pereira
da Silva, Luan Nascimento
Oliveira, Rafaella Lima
Ferreira, Teresa de Fátima Ramos
Albuquerque, Renato Adams Matos
author_sort Silva, Mayara Gabrielle Barbosa e
collection PubMed
description OBJECTIVE: To test several weaning predictors as determinants of successful extubation after elective cardiac surgery. METHODS: The study was conducted at a tertiary hospital with 100 adult patients undergoing elective cardiac surgery from September to December 2014. We recorded demographic, clinical and surgical data, plus the following predictive indexes: static compliance (Cstat), tidal volume (Vt), respiratory rate (f), f/ Vt ratio, arterial partial oxygen pressure to fraction of inspired oxygen ratio (PaO(2)/FiO(2)), and the integrative weaning index (IWI). Extubation was considered successful when there was no need for reintubation within 48 hours. Sensitivity (SE), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), and negative likelihood ratio (LR-) were used to evaluate each index. RESULTS: The majority of the patients were male (60%), with mean age of 55.4±14.9 years and low risk of death (62%), according to InsCor. All of the patients were successfully extubated. Tobin Index presented the highest SE (0.99) and LR+ (0.99), followed by IWI (SE=0.98; LR+ =0.98). Other scores, such as SP, NPV and LR-were nullified due to lack of extubation failure. CONCLUSION: All of the weaning predictors tested in this sample of patients submitted to elective cardiac surgery showed high sensitivity, highlighting f/Vt and IWI.
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spelling pubmed-47625502016-02-24 Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery Silva, Mayara Gabrielle Barbosa e Borges, Daniel Lago Costa, Marina de Albuquerque Gonçalves Baldez, Thiago Eduardo Pereira da Silva, Luan Nascimento Oliveira, Rafaella Lima Ferreira, Teresa de Fátima Ramos Albuquerque, Renato Adams Matos Braz J Cardiovasc Surg Original Article OBJECTIVE: To test several weaning predictors as determinants of successful extubation after elective cardiac surgery. METHODS: The study was conducted at a tertiary hospital with 100 adult patients undergoing elective cardiac surgery from September to December 2014. We recorded demographic, clinical and surgical data, plus the following predictive indexes: static compliance (Cstat), tidal volume (Vt), respiratory rate (f), f/ Vt ratio, arterial partial oxygen pressure to fraction of inspired oxygen ratio (PaO(2)/FiO(2)), and the integrative weaning index (IWI). Extubation was considered successful when there was no need for reintubation within 48 hours. Sensitivity (SE), specificity (SP), positive predictive value (PPV), negative predictive value (NPV), positive likelihood ratio (LR+), and negative likelihood ratio (LR-) were used to evaluate each index. RESULTS: The majority of the patients were male (60%), with mean age of 55.4±14.9 years and low risk of death (62%), according to InsCor. All of the patients were successfully extubated. Tobin Index presented the highest SE (0.99) and LR+ (0.99), followed by IWI (SE=0.98; LR+ =0.98). Other scores, such as SP, NPV and LR-were nullified due to lack of extubation failure. CONCLUSION: All of the weaning predictors tested in this sample of patients submitted to elective cardiac surgery showed high sensitivity, highlighting f/Vt and IWI. Sociedade Brasileira de Cirurgia Cardiovascular 2015 /pmc/articles/PMC4762550/ /pubmed/26934398 http://dx.doi.org/10.5935/1678-9741.20150076 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
Silva, Mayara Gabrielle Barbosa e
Borges, Daniel Lago
Costa, Marina de Albuquerque Gonçalves
Baldez, Thiago Eduardo Pereira
da Silva, Luan Nascimento
Oliveira, Rafaella Lima
Ferreira, Teresa de Fátima Ramos
Albuquerque, Renato Adams Matos
Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title_full Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title_fullStr Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title_full_unstemmed Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title_short Application of Mechanical Ventilation Weaning Predictors After Elective Cardiac Surgery
title_sort application of mechanical ventilation weaning predictors after elective cardiac surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762550/
https://www.ncbi.nlm.nih.gov/pubmed/26934398
http://dx.doi.org/10.5935/1678-9741.20150076
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