Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine

BACKGROUND: CYP2D6 is one of the most important members of the cytochrome P450 superfamily. Its genetic polymorphism significantly influences the efficacy and safety of some drugs, which might cause adverse effects and therapeutic failure. METHODS AND RESULTS: The aim of this research was mainly to...

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Detalles Bibliográficos
Autores principales: Xu, Ren-ai, Gu, Er-min, Zhou, Quan, Yuan, Lingjing, Hu, Xiaoxia, Cai, Jianping, Hu, Guoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762583/
https://www.ncbi.nlm.nih.gov/pubmed/26937172
http://dx.doi.org/10.2147/DDDT.S97789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762583/
https://www.ncbi.nlm.nih.gov/pubmed/26937172
http://dx.doi.org/10.2147/DDDT.S97789

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