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Effects of 22 novel CYP2D6 variants found in Chinese population on the metabolism of dapoxetine
BACKGROUND: CYP2D6 is one of the most important members of the cytochrome P450 superfamily. Its genetic polymorphism significantly influences the efficacy and safety of some drugs, which might cause adverse effects and therapeutic failure. METHODS AND RESULTS: The aim of this research was mainly to...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762583/ https://www.ncbi.nlm.nih.gov/pubmed/26937172 http://dx.doi.org/10.2147/DDDT.S97789 |