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Catalytic asymmetric direct aldol reaction of α-alkyl azlactones and aliphatic aldehydes
An unprecedented highly diastereoselective and enantioselective aldol reaction of α-alkyl azlactones and aliphatic aldehydes was achieved with cinchona alkaloid catalysts. To our knowledge, this reaction provides the first useful catalytic asymmetric access toward β-hydroxy-α-amino acids bearing alk...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal Society of Chemistry
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762611/ https://www.ncbi.nlm.nih.gov/pubmed/26918108 http://dx.doi.org/10.1039/c5sc02116b |