Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics

Microglia, the resident immune cells of the brain, have been shown to display a complex spectrum of roles that span from neurotrophic to neurotoxic depending on their activation status. Microglia can be classified into four stages of activation, M1, which most closely matches the classical (pro-infl...

Descripción completa

Detalles Bibliográficos
Autores principales: Bell-Temin, Harris, Culver-Cochran, Ashley E., Chaput, Dale, Carlson, Christina M., Kuehl, Melanie, Burkhardt, Brant R., Bickford, Paula C., Liu, Bin, Stevens, Stanley M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762627/
https://www.ncbi.nlm.nih.gov/pubmed/26424600
http://dx.doi.org/10.1074/mcp.M115.053926

Ejemplares similares

Ejemplares similares