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Characterization of Liver Monocytic Myeloid-Derived Suppressor Cells and Their Role in a Murine Model of Non-Alcoholic Fatty Liver Disease
Myeloid-derived suppressor cells (MDSCs) are potent suppressors of T cell immunity in tumors and inflammatory diseases. They are identified by surface expression of CD11b(+)Gr1(+) in mice, and CD11b(+)Gr1(+) cells accumulate in the livers of obese mice. However, many myeloid cells share these CD11b(...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762771/ https://www.ncbi.nlm.nih.gov/pubmed/26901500 http://dx.doi.org/10.1371/journal.pone.0149948 |