Diverse drug-resistance mechanisms can emerge from drug-tolerant cancer persister cells

Cancer therapy has traditionally focused on eliminating fast-growing populations of cells. Yet, an increasing body of evidence suggests that small subpopulations of cancer cells can evade strong selective drug pressure by entering a ‘persister' state of negligible growth. This drug-tolerant sta...

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Detalles Bibliográficos
Autores principales: Ramirez, Michael, Rajaram, Satwik, Steininger, Robert J., Osipchuk, Daria, Roth, Maike A., Morinishi, Leanna S., Evans, Louise, Ji, Weiyue, Hsu, Chien-Hsiang, Thurley, Kevin, Wei, Shuguang, Zhou, Anwu, Koduru, Prasad R., Posner, Bruce A., Wu, Lani F., Altschuler, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762880/
https://www.ncbi.nlm.nih.gov/pubmed/26891683
http://dx.doi.org/10.1038/ncomms10690

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