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Antibody-based PET imaging of amyloid beta in mouse models of Alzheimer's disease

Owing to their specificity and high-affinity binding, monoclonal antibodies have potential as positron emission tomography (PET) radioligands and are currently used to image various targets in peripheral organs. However, in the central nervous system, antibody uptake is limited by the blood–brain ba...

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Detalles Bibliográficos
Autores principales:	Sehlin, Dag, Fang, Xiaotian T., Cato, Linda, Antoni, Gunnar, Lannfelt, Lars, Syvänen, Stina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762893/ https://www.ncbi.nlm.nih.gov/pubmed/26892305 http://dx.doi.org/10.1038/ncomms10759

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