LGR5 rs17109924 is a predictive genetic biomarker for time to recurrence in patients with colon cancer treated with 5-fluorouracil-based adjuvant chemotherapy

We recently found variants in cancer stem cell genes (CD44, ALCAM and LGR5) significantly associated with increased time to recurrence (TTR) in patients with stage III and high-risk stage II colon cancer treated with 5-fluorouracil (5-FU)-based chemotherapy. In this study, we validated these genetic...

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Detalles Bibliográficos
Autores principales: Szkandera, J, Herzog, S, Pichler, M, Stiegelbauer, V, Stotz, M, Schaberl-Moser, R, Samonigg, H, Asslaber, M, Lax, S, Leitner, G, Renner, W, Lenz, H-J, Berghold, A, Gerger, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762902/
https://www.ncbi.nlm.nih.gov/pubmed/25665511
http://dx.doi.org/10.1038/tpj.2015.2

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