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Establishing the characteristics of an effective pharmacogenetic test for clozapine-induced agranulocytosis
Clozapine is the only evidence-based therapy for treatment-resistant schizophrenia, but it induces agranulocytosis, a rare but potentially fatal haematological adverse reaction, in less than 1% of users. To improve safety, the drug is subject to mandatory haematological monitoring throughout the cou...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762904/ https://www.ncbi.nlm.nih.gov/pubmed/25732907 http://dx.doi.org/10.1038/tpj.2015.5 |