Non-monotonic Response to Monotonic Stimulus: Regulation of Glyoxylate Shunt Gene-Expression Dynamics in Mycobacterium tuberculosis

Understanding how dynamical responses of biological networks are constrained by underlying network topology is one of the fundamental goals of systems biology. Here we employ monotone systems theory to formulate a theorem stating necessary conditions for non-monotonic time-response of a biochemical...

Descripción completa

Detalles Bibliográficos
Autores principales: Ascensao, Joao A., Datta, Pratik, Hancioglu, Baris, Sontag, Eduardo, Gennaro, Maria L., Igoshin, Oleg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762938/
https://www.ncbi.nlm.nih.gov/pubmed/26900694
http://dx.doi.org/10.1371/journal.pcbi.1004741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762938/
https://www.ncbi.nlm.nih.gov/pubmed/26900694
http://dx.doi.org/10.1371/journal.pcbi.1004741

Ejemplares similares