A Novel Synthetic TLR-4 Agonist Adjuvant Increases the Protective Response to a Clinical-Stage West Nile Virus Vaccine Antigen in Multiple Formulations

West Nile virus (WNV) is a mosquito-transmitted member of the Flaviviridae family that has emerged in recent years to become a serious public health threat. Given the sporadic nature of WNV epidemics both temporally and geographically, there is an urgent need for a vaccine that can rapidly provide e...

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Detalles Bibliográficos
Autores principales: Van Hoeven, Neal, Joshi, Sharvari Waghmare, Nana, Ghislain Ismael, Bosco-Lauth, Angela, Fox, Christopher, Bowen, Richard A., Clements, David E., Martyak, Timothy, Parks, D. Elliot, Baldwin, Susan, Reed, Steven G., Coler, Rhea N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4762984/
https://www.ncbi.nlm.nih.gov/pubmed/26901122
http://dx.doi.org/10.1371/journal.pone.0149610

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